The Entourage Effect & Ratios


Cannabis therapeutics is personalized medicine. The right treatment regimen depends on the person and the condition being treated. The discovery of CBD’s potential medical benefits coupled with its non-psychoactive nature enabled consumers all over the world to easily access CBD derived from hemp. With more states legalizing medical cannabis use and increased research on the plant, scientists have discovered that there is a significant difference between isolating cannabinoids, like CBD, from the rest of the compounds produced in the plant, as well as maintaining the chemical integrity of the plant-- which naturally boosts the effects and benefits of these compounds. What is commonly referred to as “the entourage effect”, the hundreds of chemicals that are produced naturally within the plant (such as cannabinoids and terpenes) contribute to the overall effects and medical benefits of a particular strain.

Although CBD alone may be effective for some patients, the THC produced in the marijuana plant may boost the effects of CBD. CBD is available in a variety of forms: 1:1, 2:1, 3:2, 5:1, 10:1, 20:1, etc. The lower the THC ratio compared to CBD is, the less likely it may be to be psychoactive. However, even in a relatively even 1:1 CBD:THC ratio, the psychoactive effects of THC may be countered by CBD, providing a more controlled and subtler effect for some patients.

Potent cannabis oil extracts can have varying ratios of CBD and THC which are calibrated to suit the needs and sensitivities of each patient. For anxiety, depression, spasms, and pediatric seizure disorders, many patients initially may find they do best with a moderate dose of a CBD-dominant remedy. However, a low THC remedy may not necessarily the best therapeutic option for others. Extensive research has shown that a 1:1 CBD THC ratio is effective for neuropathic pain. Optimizing one’s therapeutic use of cannabis may entail a careful step by step process. Oftentimes results are seen through a trial and error process as all endocannabinoid systems are unique. It may take some time to find the optimal dose that works best for each individual and their condition.

Graphic By: www.leafscience.com

For more information about the entourage effect, visit Leafly.com.